Wednesday, March 7, 2007

"The Mind's Mirror" Summary

Journal 12: Summary 6:

I have discussed before in my “research, research everywhere…” post my issues with being able find sources, but many of them have the same information. It is similar in this source, however there is a good bit of new mixed in with all of the old information so, although this may be little shorter than normal, I will only summarize the new and more relevant issues discussed in this article. This article written by Lea Winerman discusses an aspect that has been slightly allusive to me until now. She discusses a study done by Marco Iacoboni in which mirror neurons were shown to be used in determining intention. In the study, the participants were shown a video of a woman at a tea party picking up her cup. Then they were shown a video of the same tea party with crumbs and dishes scattered on the table indicating it was over. The same woman was shown picking up her cup in this context as well. Finally the cup was shown alone in no context. The EEG results showed much more activity in the mirror neuron area during the videos of the tea party than when the cup was removed from context. This shows that the brain was working more to recognize that in the first video the woman was lifting the cup to drink from it and in the second video she was lifting it to clean it. Less brain stimulation occurred during the video of the cup out of any context. The brain worked less to recognize a simple picture on a screen than it did when processing intention and context. "This suggests that the neurons are important for understanding intentions as well as actions," Iacoboni says. Vittorio Gallese, MD, PhD, at the University of Parma is very experienced with mirror neurons and has this to say about their importance in society “This neural mechanism is involuntary and automatic, with it we don't have to think about what other people are doing or feeling, we simply know. It seems we're wired to see other people as similar to us, rather than different. At the root, as humans we identify the person we're facing as someone like ourselves."

Works cited:

Winerman, Lea. “The Mind’s Mirror”. APA Online . Volume 36, No. 9 October 2005. 7 Mar. 2007. < http://www.apa.org/monitor/oct05/mirror.html>

Friday, March 2, 2007

Research, Research Everywhere, but not a Source to Cite

Journal 11:

Type into Google ‘Mirror Neurons’ and see how many results pop up. 927,000 to be exact. This could give an indication of how much information there is on the subject, but to delve a bit deeper we must actually click on some of these 927,000 results. The name Vilayanur Ramachandran , now deeply encoded into my long term memory banks, is everywhere on these sites. He is the leading researcher in this area and is one of the only experts in these particular neurons. Several studies have been done in the United States and several more in countries ahead in neuroscience technologies like China, the United Kingdom, Iceland, Switzerland and Canada. All of the studies done, even with a very wide variety of variables, have the same conclusion. In 80% of the tested individuals with autism spectrum disorders a malfunction in their mirror neuron system is exposed. Many of the sources found using Google are accounts, summaries, and results from these same handful of experiments. Because of the similarity in procedure and results of these studies I am having a lot of trouble finding new sources to use that will not make all of my papers the same drone of information just presented in a different box with a new shinny bow. There is plenty of support for the theory, but not a lot of unique views on the subject because the topic is still relatively new to researchers. However, type ‘autism’ into Google and over 16,600,000 results come out. In discussing the implications of mirror neurons in autism I must establish what autism is and why mirror neurons could be a large piece of the puzzle in some cases of autism. There is not a set standard for what exactly autism is and I will need to discuss that in great detail in my paper. I believe that with expansion and explanation, I can easily write an eight page paper discussing this topic extensively without struggling.

“Inside the Autistic Mind" Summary

Journal 10: Summary 5:

I for one have always been a fan of Time Magazine. No matter what the subject the writers at Time have always had a way of drawing me in and fixing my mind to whatever it is the article is about. This article “Inside the Autistic Mind” by Claudia Wallis is no different. Although the article disagrees with much of what I have been researching I feel that it is necessary to include this point of view in my sources and in my paper. The article begins with a short introduction to a young girl named Hannah. Hannah has a relatively strong case of autism and for the first thirteen years of her life was unable to speak beyond a few repeated phrases. Wallis describes in beautiful detail the groundbreaking moment that Hannah made contact with her outside world for the first time. Using a method called facilitated communication, a system using a keyboard and a facilitator to help controll the communication, Hannah was able to tell her mother that she loves her. Facilitated communication has been the subject of some controversy. Those who appose this method say that the person helping to control the communication is really the one creating the communication, but with Hannah at the keyboard it is clear that her life has been changed. Shortly after this first emotional outreach, Hannah is now learning algebra, biology, and history. Hannah, now nearly 15, is dealing with being autistic in a way that many cannot. With her keyboard she is able to communicate her feelings about being autistic and the nearly 13 years of her life she spent in silence. She writes “Reality hurts.” Although the emotions are difficult for her to handle, Hannah is able to explain her actions and abilities and offer insight into the autistic disorder. For example Hannah explains why she does not look at things directly but rather she uses her peripheral vision to see because her sight is overly sensitive to light.She also has a hypersensitive sense of hearing, being able to hear things at one end of their home that is happening on the other side. Also it has been discovered that Hannah has some very unique gifts. Upon being given a list of 30 math questions Hannah immediately typed the answers to all 30. Hannah has a photographic memory.

Wallis continues on to explain “Autism is almost certainly, like cancer, many diseases with many distinct causes. It's well known that there's a wide range in the severity of symptoms--from profound disability to milder forms like Asperger syndrome, in which intellectual ability is generally high but social awareness is low. Indeed, doctors now prefer the term Autistic Spectrum Disorders (ASD). But scientists suspect there are also distinct subtypes, including an early-onset type and a regressive type that can strike as late as age 2.” She describes that many problems in the brain are found in autistic individuals; problems with neurons (like mirror neurons), oversized areas, disconnections between lobes, and many other irregularities, but it is difficult to pinpoint weather these abnormalities came about because of the autistic disorder or if they are what caused it. Furthermore other symptoms are beginning to be dispelled, like inability to love or lack of emotional connections thanks to cases like Hannah’s. Also symptoms like spinning, head banging, and repetition appear to be more a way of coping then just a physical symptom. A quote used later in the article brings some insight into the reason for these actions “Chandima Rajapatirana, an autistic writer from Potomac, Md., offers this account: ‘Helplessly I sit while Mom calls me to come. I know what I must do, but often I can't get up until she says, 'Stand up,'. [The] knack of knowing where my body is does not come easy for me. Interestingly I do not know if I am sitting or standing. I am not aware of my body unless it is touching something ... Your hand on mine lets me know where my hand is. Jarring my legs by walking tells me I am alive.’”

Further more, other possible causes for autism have been discussed, like high levels of mercury in the body, but no one cause can be singled out. Researchers believe that there is a combination of genetic and environmental factors implicated in the cause of autism. Genetic factors have been long studied and Wallis explains “An identical twin of a child with autism has a 60% to 90% chance of also being affected. And there's little doubt that a vulnerability to ASD runs in some families: the sibling of a child with autism has about a 10% chance of having ASD”. There have been abnormalities found on chromosomes 2, 5, 7, 11 and 17 and as David Amaral, research director of the MIND (Medical Investigation of Neurodevelopmental Disorders) Institute, says “We think there are a number of different autisms, each of which could have a different cause and different genes involved,". Regardless of the causes, over 300,000 school age children suffer from the effects of this disorder all in their own ways. The most upsetting cases are those like Hannah’s. Those who “have a lively intelligence trapped in a body that makes it difficult for others to see that the lights are on.” Or a boy stricken with a very severe case of autism; nable to speak or sustain his attention from one moment to the next, yet this boy is tragically aware of his situation. As Wallis writes “How many other autistic kids, Merzenich wonders, ‘are living in a well where no one can hear them’?” For some like Hannah, who is now preparing for college, life after so many years of silence can become a cacophony of happiness. But still some remain in silence waiting for us to breakthrough that two-way mirror. We have come so far in scientific breakthroughs and perhaps the answers are right around the corner, but for now we will continue doing everything in our power for those suffering from autism.

Works cited:

Wallis, Claudia . “Inside the Autistic Mind”. Time 7 May 2006. 1 Mar. 2007

Thursday, March 1, 2007

Peer review sessions 2/8 and 2/22

Journal 9:

I admit I have been slightly neglecting my blog of lately and (admittedly because the professor said she is checking blogs this weekend) I need to catch up. I am a little unclear on what exactly I am missing from my blog, but upon checking other blogs I have realized that a lot of other people used an explanation of peer review days as an entry and I will be doing the same. It may be a little out of order but better late that never.

Peer review 2/8: Important figures paper

I began on the day we did our first peer review. After giving my papers to Shelly and Ann I stressed to them my extreme misuse of the comma. I have always been comma happy in my writing and recently, due to being screamed at for using to many commas, I have been neglecting comma use in my papers. I reread the chapter on commas and even though I enjoy the comical styling of our Grammar and Style book, but it was not of the utmost help. It could just be that I am comma stupid and incapable of grasping the enigma that is the comma. Anyways, after a long silence during which much reading occurred, Ann was the first to discuss my paper. She started with a compliment saying that I had done a nice job with only some minor mistakes. She pointed out a run-on sentence in my first paragraph, an awkward sentence and an unclear explanations in my second, and some capitalization problems in my third. The main thing she showed me was my works cited page. I had forgotten (because it has been quite a long time since I have written a WC page) to use a hanging indent. Mrs. Mangun (my really cool Senior year English teacher) would be kicking me in the head if she saw my works cited page. It was a mess. Next to review my paper was Shelly. Shelly I could tell was a bit shy when it comes to reviewing other peoples work. She is very nice and I think kind of afraid to offend someone if she points out errors so she only a few things about missing commas and unclear passages to show me but it was still very helpful to me. My session went very well and I appreciated what both the girl had to say about my paper. Next Ann gave us her paper and explained that she had misunderstood the assignment so the paper was not exactly on the right subject but to just go with the flow and so we read her paper. I went first when I was done reading her paper. Other than not being on the right subject it was very well written. He had a nice flow and a good tone in her writing. I pointed out some repetitive words and awkwardly sounding sentences but honestly there was not much there to correct ( I was not just being lazy). Last but not least we read Shelly’s paper. Her topic is the Wright brothers and their role in aviation so it was a pretty interesting paper and enjoyable to read. Ann went first this time and pointed out many of the things I had noticed as well. Some minor punctuation and awkward sentences, but when it was my turn I pointed out her quotes. She had quoted some thing that really didn’t need to be quoted and some stuff that that I though needed to be paraphrased and not quoted. I did my best in the short time we had left in class to explain the rules for quoting and citations and her works cited page. I ended up commenting on her blog with some more helpful information because we did not have much time left in class by the time we got to her paper. Overall, Shelly’s paper was very well written as well. She has a unique writing style and an interesting topic. All together I think the peer review session was helpful to everyone and we used the class time well.

Peer review session 2/22: Important issues paper

This peer review session was a little mixed up due to the fact that we only had 5 people at the beginning of class, so we all traded papers as one big group. No one really said anything about their papers before we began reading so I kind of said to anyone listening my spiel about my paper. I had been rushed that week to finish my paper and barley got 2 ½ pages done for the peer review. I explained that the paper was not completely coherent because I jot down ideas and write as ideas come to me and then go back and add and fix stuff later and I had not had enough time to completely add and fix things. I had 3 papers to read and everyone else had 3 or 4 each so we took a lot of time reading (nearly ¾ the class time) and slowly we all started handing back papers and chattering quietly. Mostly we all just commented on the sides of the paper and Ms. Hanes lectured us on citations and using Wikipedia as a source so we really did not have time to talk to each other about our comments, but I talked to Shelly and Casey about their papers before I left. I got a lot of good comments on my papers even tough we didn’t all talk. I think this class session went well also.

Tuesday, February 27, 2007

"Understanding Autism: Insights from Mind and Brain" Summary

Journal 8: Summary 4:

To further explore the Theory of Mind deficit in autistic individuals we must look further into what theory of mind is. Theory of Mind (ToM) is a persons ability to attribute mental and emotional states to themselves and to others. In autism it has been widely agreed that a fully developed ToM is missing . Autistic children have trouble understanding purpose and emotion in situations. In tests done by Baron-Cohen et al on normally functioning four year old individuals, autistic individuals with a mental state of about four years old, and individuals with down syndrome, they were told a story about two girls. One girl placed a marble into a basket and then leaves the room. Then the other girl takes the marble while the first girl is away and places it into her box. The first girl then comes back. The participants were asked where girl number one would look for her marble. The group of normally functioning individuals answered that the girl would look into her basket for the marble because she did not know it was not in the basket. However 80% of the autistic individuals answered that she would look into the box, even though they answered that the second girl had put the marble in her basket and she did not know it had been moved. Furthermore 86% of the individuals with down syndrome answered correctly. This test shows an obvious deficit in ToM in the autistic individuals. Many theories have been devised concerning the reason for this deficit including but not limited to the mirror neuron theory.

Works cited:

Hill,;Elisabeth L.Frith,Uta "Understanding Autism: Insights from Mind and Brain"
Philosophical Transactions: Biological Sciences, Vol. 358, No. 1430, Autism: Mind and Brain. (Feb. 28, 2003), pp. 281-289.

Monday, February 26, 2007

Using the Mirror Neuron Theory for early diagnosis and therapies for autism

Journal 7:

So far in this blog I have only discussed the evidence for the existence of a mirror neuron system and its correlation to symptoms of autism, but what I have not yet discussed could possibly be the most important aspect; the reason the research has been conducted in the first place; finding a cure, or at least being able to further diagnosis and therapies for those suffering from the disorder. Due to the fact that these theories are fairly new and testing takes a great deal of time, only educated hypotheses can be made for possible treatments at this time, but I think it is important to include these possibilities into my research as the next steps to be taken in this field.

First, the possibility of early diagnosis comes from the EEG machine. In the experiment described in an earlier post, where EEG machines were used to detect the responses of the mirror neuron system to stimuli, the objects being detected were called Mu waves. A Mu wave is one of many Electromagnetic waves in the brain ranging from 8-13 Hertz. These Mu waves “arise from synchronous and coherent electrical activity of large groups of neurons in the human brain”. The waves are measurable with an electroencephalography or (EEG) machine. Many tests have been done observing the Mu waves with the EEG machine and it has been found that the Mu waves in the brain are suppressed when a person makes a voluntary movement. Also, it has been noted that the Mu waves are suppressed when watching someone else perform a task as well. In autistic individuals the mu waves are suppressed when doing an action, but not when seeing an action done. These findings suggest that EEG machines can be used to diagnose autism within weeks of birth. EEG machines pose no risk to infants, although it may be a little difficult to get a newborn to stop struggling long enough to put the cap on. Earlier diagnosis of autism means many things in the autism community. A few advantages of early diagnosis are early therapies and interventions and an understanding of the learning difficulties associated with autism. This could also mean great leaps forward in the way autism education is approached.

There have been many suggested therapies with these new theories that could lead to better treatment options for autistic individuals as well. One such suggestion is biofeedback. Basically, biofeedback could be used to “used to display the mu waves and then use visual feedback of the display of the mu waves to teach children how to suppress the mu waves.” very little research has been published in this area, but still more is being conducted. The few published studies show very promising results with improvements in almost all areas using biofeedback.

Another possibility is correcting a chemical imbalance that may be disabling the mirror neuron system. Researchers believe that using certain neuromodulators could stimulate the mirror neurons that are associated with emotional responses; an area affected greatly in autism spectrum disorders. These along with many other innovative ideas are in testing right now and results seem to be very promising.


Works Cited:

“Mirror Neuron Theory”. Nov. 2006. 21 Feb. 2007

Olds, Jim. Krasnow Director's Column. 23 Oct.2006 . 26 Feb. 2007

What’s New in Neurofeedback. Kaiser,David. July. 2006. Vol. 9 No. 7 26 Feb. 2007.

Sunday, February 11, 2007

"Imitation, mirror neurons, and autism" Summary :

Journal 6: Summary 3:

One commonly associated deficit in autism is an absence of ‘theory of mind’. The theory of mind or ToM as defined by Premack and Woodruff, who first described this theory in 1978, as the ability to “attribute mental states and to use these invisible postulates to explain behavior in everyday life”( Qtd. In Chari). In a broader definition as described by Encarta MSN.com’s dictionary ToM is “concepts of mental activity: the way somebody conceives of mental activity in others, including how children conceptualize mental activity in others and how they attribute intention to and predict the behavior of others”. The problem with trying to use the ToM exclusively to explain autism is that some major symptoms, such as an inability to imitate other people and delays in or a complete lack of language development seem to either counter or steam from somewhere else completely than the ToM.

To account for this seeming discrepancy we must examine imitation as a precursor for a theory of mind. You must first be able to imitate something; to see someone do and then do yourself, before you are able to breakdown in your own mind the possibility of what and why they have done this, thus being able to understand the doer’s situation and apply it to their own lives. To apply this to a deficit of ToM in autism we can show a deficit in imitation. In 21 studies done, 19 showed at least some level of an inability or unwillingness to readily imitate other humans in autistic individuals. These findings suggest a problem with the ability of the individuals to properly map the actions of others.

Patients with damage to their front left lobe of their brain have shown huge deficits in their ability to imitate actions, though they have the physical ability to. This coincides with the idea that imitation relies on the representations of actions and is associated with the part of the brain that has been damaged in these individuals. This area has been studied in non-human primates and a system of neurons called the mirror neuron system (MN system) has been discovered, which is responsible for coding the actions of the primates. It is not possible to directly study humans in the same way as these primates to show the sure existence of a mirror neuron system in humans, but EEG tests strongly suggest such a discovery.

Mirror neurons involving hand motions in primates are thought to have evolved into speech capabilities in humans, and thus “by acting as a bridge between perceived and performed actions and speech, the MN system is thus suggested to have provided the foundations for the evolution of dialogue”. The mirror neuron system is also associated with the ability to ‘put yourself into someone else’s shoes,’ and as stated earlier, this is associated with the development of a theory of mind.

All of this can be applied in autism by showing a malfunction in the mirror neuron system. I have already discussed the studies described here for showing the disjunction in mirror neurons in autistic individuals so I will not describe them again. (refer to posts 2 and 4 for explanations).

There is no empirical evidence that the existence of a MN system is utilized in imitation and thus the development of a theory of mind and that a dysfunction in the MN system can lead to the autism, but the evidence presented thus far can strongly suggest such a conclusion.


Works Cited:

Chari, Satyan. “The “Theory of Mind” Hypothesis: Explaining Autism”. 2003. 10 Feb. 2007

Encarta World English Dictionary [North American Edition], 2006. Bloomsbury Publishing Plc. 10 Feb. 2007

Williams, J.H.G, Whiten, A, Suddendorf, T, Perrett, D.I. Rev. of Imitation, mirror neurons, and autism. 19 Mar. 2001. 10 Feb. 2007